p38 MAPK Inhibitors

p38 MAPK

Akt1

p38α

p38β

MAPK13

p38δ

p38γ

p38 MAPK Inhibitors, Agonists, Activators, p53 Inhibitors, Degraders & Ligands

Product Name	p38 MAPK	Akt1	p38α	p38β	MAPK13	p38δ	p38γ	Purity
Adezmapimod	p38, IC₅₀: 50 nM			p38β2, IC₅₀: 500 nM				99.91%
SB 202190			p38α, IC₅₀: 50 nM	p38β2, IC₅₀: 100 nM				99.89%
Anti-inflammatory agent 99	p38
Doramapimod	p38 MAP kinase, Kd: 0.1 nM		p38α, IC₅₀: 38 nM	p38β, IC₅₀: 65 nM		p38δ, IC₅₀: 520 nM	p38γ, IC₅₀: 200 nM	99.98%
Muramyl dipeptide	p38 MAPK							99.07%
Adezmapimod hydrochloride	p38, IC₅₀: 50 nM			p38β2, IC₅₀: 500 nM				99.71%
Diprovocim	p38 MAPK							98.82%
Naporafenib			p38α, IC₅₀: 2.1 μM					99.92%
Ralimetinib dimesylate			p38α MAPK, IC₅₀: 5.3 nM	p38β MAPK, IC₅₀: 3.2 nM				99.97%
Neflamapimod			p38α, IC₅₀: 10 nM	p38β, IC₅₀: 220 nM				99.32%
Esculin	p38 MAPK							99.85%
Skatole	p38							99.99%
Exarafenib	p38 MAPK							99.68%
SB 202190 hydrochloride			p38α, IC₅₀: 50 nM	p38β2, IC₅₀: 100 nM				99.60%
Dihydrocaffeic acid	p38 MAPK							99.86%
p38 MAPK-IN-1	p38 MAPK, IC₅₀: 68 nM							99.71%
Peimine	p38							99.9%
Paris saponin VII	p38							99.84%
Teneligliptin hydrobromide	p38 MAPK							99.99%
Gossypetin	p38 MAP kinase							99.82%
MAPK13-IN-1					MAPK13 (p38δ), IC₅₀: 620 nM			98.88%
AMG-548 dihydrochloride			p38α, Ki: 0.5 nM dog p38α, Ki: 5.0 nM	p38β, Ki: 3.6 nM		p38δ, Ki: 2600 nM	p38γ, Ki: 4100 nM	99.86%
Talmapimod			p38α, IC₅₀: 9 nM	p38β, IC₅₀: 90 nM				98.68%
TAK-715			p38α, IC₅₀: 7.1 nM	p38β, IC₅₀: 200 nM		p38δ, IC₅₀: >10 μM	p38γ, IC₅₀: >10 μM	99.76%
Isobavachin	p38 MAPK							99.88%
2"-O-Galloylhyperin	p38							99.57%
Tpl2 Kinase Inhibitor 1	p38, IC₅₀: 180 μM							99.42%
Callistephin chloride	p38							98.31%
Broussonin E	p38 MAPK							98.11%
Semapimod tetrahydrochloride	p38 MAPK							99.18%
Ferulic acid methyl ester	p38							99.95%
Pamapimod			p38α, IC₅₀: 14 nM p38α, Ki: 1.3 nM	p38β, IC₅₀: 480 p38β, Ki: 120 nM				99.71%
Maackiain	p38 MAP kinase							99.83%
AMG-548			p38α, Ki: 0.5 nM dog p38α, Ki: 5.0 nM	p38β, Ki: 3.6 nM		p38δ, Ki: 2600 nM	p38γ, Ki: 4100 nM	≥99.0%
SR-318			p38α, IC₅₀: 5 nM	p38β, IC₅₀: 32 nM				98.17%
Cornuside	p38 MAP kinase							99.99%
NF-κB/MAPK-IN-1	p38							98.71%
UM-164			p38α	p38β				98.74%
SM-7368	p38 MAP kinase							99.77%
Duligotuzumab	p38 MAPK							99.17%
Rotundic acid	p38 MAPK							99.41%
N-(p-Coumaroyl) Serotonin	p38 MAPK							99.03%
SJF-8240			p38α					99.33%
Isoliquiritin apioside	p38 MAPK							99.87%
R1487 Hydrochloride			p38α, Kd: 0.2 nM	p38β, Kd: 29 nM				98.96%
CK1-IN-1			p38α MAPK, IC₅₀: 73 nM					99.19%
EW-7195			p38α, IC₅₀: 1.5 μM					98.84%
Armepavine	p38 MAPK							99.53%
Ralimetinib			p38α MAPK, IC₅₀: 5.3 nM	p38β MAPK, IC₅₀: 3.2 nM				98.58%
MKK7-COV-9	p38 MAP kinase
RWJ-67657			p38α, IC₅₀: 1 μM	p38β, IC₅₀: 11 μM				99.75%
TA-01	p38 MAP kinase, IC₅₀: 6.7 nM							99.86%
JNJ-49095397			p38α				p38γ	99.55%
Viridicatol	p38 MAPK							99.93%
SB 220025	p38, IC₅₀: 60 nM							99.90%
MW-150			p38α, Ki: 101 nM					99.89%
p38α inhibitor 2			p38α MAPK, pIC₅₀: 9.6					98.33%
p38 MAP Kinase Inhibitor III	p38 MAP kinase, IC₅₀: 0.9 μM							98.77%
Emprumapimod			p38α					99.39%
BMS-582949 hydrochloride			p38α MAPK, IC₅₀: 13 nM					98.90%
p38 MAP Kinase Inhibitor IV			p38α, IC₅₀: 0.13 μM	p38β, IC₅₀: 0.55 μM		p38δ, IC₅₀: 8.63 μM		99.0%
Isoastragaloside I	p38 MAP kinase							99.49%
SD-169			p38α MAPK, IC₅₀: 3.2 nM	p38β MAPK, IC₅₀: 122 nM				99.17%
p38 MAPK-IN-4	p38, IC₅₀: 35 nM							98.69%
SJFα			p38α, DC₅₀: 7.16 nM			p38δ, DC₅₀: 299 nM		99.61%
PF-03715455			p38α, IC₅₀: 0.88 nM	p38β, IC₅₀: 23 nM				98.44%
Casuarinin	p38 MAPK							98.24%
Sugiol	p38 MAPK							99.88%
Undecane	p38							99.66%
Cathepsin G	p38 MAPK
YS110	p38 MAPK							99.14%
Hecogenin acetate	p38 MAPK							98.57%
Vitexin-4''-O-glucoside	p38							99.86%
SR-302			p38α, IC₅₀: 125 nM					98.51%
p38α inhibitor 1			p38α					98.91%
Org 48762-0			p38α, EC₅₀: 0.1 nM					99.99%
Satratoxin H	p38 MAPK							99.7%
SX 011			p38α, IC₅₀: 9 nM	p38β, IC₅₀: 90 nM		p38δ, IC₅₀: > 300,000 nM	p38γ, IC₅₀: > 300,000 nM	99.33%
PF-05381941			p38α, IC₅₀: 186 nM					99.73%
AL 8697			p38α, IC₅₀: 6 nM	p38β, IC₅₀: 82 nM				99.92%
SJFδ			p38α, DC₅₀: 46.17 nM
Emprumapimod hydrochloride			p38α					98.0%
NR-11c			p38α					99.75%
Anti-inflammatory agent 35	p38 MAPK							99.77%
MW-150 hydrochloride			p38α, Ki: 101 nM
MW-150 dihydrochloride dihydrate			p38α, Ki: 101 nM
Talmapimod hydrochloride			p38α, IC₅₀: 9 nM	p38β, IC₅₀: 90 nM
ZAK-IN-2	p38
Cm-CATH2	p38
Casein kinase 1δ-IN-27			p38α, IC₅₀: 14.8 nM
p38-α MAPK-IN-4			p38α MAPK, IC₅₀: 1.5 μM
p38α-IN-11	p38, Kd: 586 nM
BChE/p38-α MAPK-IN-1			p38α MAPK, IC₅₀: 191 nM
G721-0282	p38							99.96%
Casein kinase 1δ-IN-29			p38α, IC₅₀: 0.041 μM
Halociline	p38 MAP kinase
N-Acetyldehydroanonaine		Akt1
rel-Talmapimod hydrochloride			p38α MAPK, IC₅₀: 9 nM	p38β MAPK, IC₅₀: 90 nM
p38-α MAPK-IN-5			p38α, IC₅₀: 0.1 nM	p38β, IC₅₀: 0.2 nM		p38δ, IC₅₀: 4100 nM	p38γ, IC₅₀: 944 nM
BIRB-1017	p38 MAP kinase
R-03201195	p38 MAP kinase
p38 MAPK-IN-3			p38α MAPK
R-130823			p38α, IC₅₀: 22 nM	p38β, IC₅₀: 820 nM
Pan-RAS-IN-8	p38 MAPK
SB-284851-BT			p38α, Kd: 0.47 nM
J-1149			p38α MAPK
p38α inhibitor 7			p38α
MW108 hydrochloride			p38α MAPK, Ki: 114 nM
p38α-MK2-IN-1			p38α
DCZ19931	p38 MAPK
Lucidone	p38 MAPK
Candidone	p38
AMG-548 hydrochloride			p38α, Ki: 0.5 nM dog p38α, Ki: 5.0 nM	p38β, Ki: 3.6 nM		p38δ, Ki: 2600 nM	p38γ, Ki: 4100 nM
Cryptolepine	p38 MAPK
INH2BP	p38 MAPK
CHMFL-ABL-053	p38, IC₅₀: 62 nM
Semapimod	p38 MAPK
NDs-IN-1	p38 MAPK
(aS)-PH-797804			p38α, IC₅₀: 26 nM	p38β, IC₅₀: 102 nM
Norkurarinol	p38
TOP1362			p38α
BMS-626531			p38α MAPK
JNK3 inhibitor-5			p38α, IC₅₀: 215.8 nM
p38-α MAPK-IN-11			p38α, IC₅₀: 43 nM	p38β, IC₅₀: > 100 nM		p38δ, IC₅₀: 48.6 mM	p38γ, IC₅₀: > 100 nM
Doramapimod (GMP)			p38α, IC₅₀: 38 nM	p38β, IC₅₀: 65 nM		p38δ, IC₅₀: 520 nM	p38γ, IC₅₀: 200 nM
Pleurocidin	p38 MAPK							98.91%
Isostrictiniin	p38
ARRY-371797			p38α MAPK, IC₅₀: 0.13 μM
MAPK-IN-5	p38
Tpl2 Kinase Inhibitor 1 hydrochloride	p38, IC₅₀: 180 μM
BMS-582949			p38α, IC₅₀: 13 nM
Q-Peptide	p38 MAPK							99.46%
CK1δ-IN-9			p38α, IC₅₀: 0.25 μM	p38β, IC₅₀: 0.78 μM
Hydrostatin-TL1	p38
Cudraflavone B	p38 MAP kinase
p38α inhibitor 4			p38α, IC₅₀: 1.2 μM
Casein kinase 1δ-IN-31			p38α, IC₅₀: 18 nM
p38α inhibitor 8			p38α, IC₅₀: 0.21 μM
p38-α MAPK-IN-10			p38α, IC₅₀: 4 nM
(3S)-Tanzisertib hydrochloride			p38α, IC₅₀: 3.4 μM
N-(p-Coumaroyl) Serotonin (Standard)	p38 MAPK
Balanophonin	p38
Sudachitin	p38 MAPK
Cavidine	p38
2"-O-Galloylhyperin (Standard)	p38 MAPK

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